Acid etching and plasma sterilization fail to improve osseointegration of grit blasted titanium implants.
Link: http://www.ncbi.nlm.nih.gov/pubmed/22962567
Open Orthop J. 2012;6:376-82. doi: 10.2174/1874325001206010376. Epub 2012 Sep 3.
Saksø M1, Jakobsen SS, Saksø H, Baas J, Jakobsen T, Søballe K.
Abstract
Interaction between implant surface and surrounding bone influences implant fixation. We attempted to improve the bone-implant interaction by 1) adding surface micro scale topography by acid etching, and 2) removing surface-adherent pro-inflammatory agents by plasma cleaning. Implant fixation was evaluated by implant osseointegration and biomechanical fixation.The study consisted of two paired animal sub-studies where 10 skeletally mature Labrador dogs were used. Grit blasted titanium alloy implants were inserted press fit in each proximal tibia. In the first study grit blasted implants were compared with acid etched grit blasted implants. In the second study grit blasted implants were compared with acid etched grit blasted implants that were further treated with plasma sterilization. Implant performance was evaluated by histomorphometrical investigation (tissue-to-implant contact, peri-implant tissue density) and mechanical push-out testing after four weeks observation time.Neither acid etching nor plasma sterilization of the grit blasted implants enhanced osseointegration or mechanical fixation in this press-fit canine implant model in a statistically significant manner.
KEYWORDS:
Acid etching; biocompatibility; endotoxin; grit blasting; implant surgery; plasma sterilization; titanium.
PMID: 22962567 PMCID: PMC3434975 DOI: 10.2174/1874325001206010376
Figure 3: SEM pictures of the implant surfaces: In picture D, crystals of aluminum oxide (Al2O3 particles) from the grit blasting are clearly visible.
